Virtual Microscopy	Choose another topic Cardiovascular Respiratory Renal and Urinary Tract Musculoskeletal Neuro(CNS and PNS) Gastrointestinal Reproductive Endocrine Hematopoiesis and Lymphoid Skin

Case 1:

A thirty-year-old woman presents at 34 weeks gestation for a routine OB appointment. On examination she has an elevated blood pressure and had protein detected in her urine. Following labor induction at 36 weeks she delivered a healthy 7 pound 3-ounce female infant. Examination of the placenta revealed the following: [infarct – gross] [infarct – gross] [infarct – microscopic] [infarct – microscopic]

1. How do the patient’s increased blood pressure and urine protein relate to the changes identified in the placenta?
2. Do placental infarcts occur in normal full-term placentas? If so, how do they differ from those in patients with pre-eclampsia and eclampsia?

Case 2:

A 26 year old woman delivers a 6 pound 8 ounce male infant at 34 weeks gestation following premature rupture of membranes. The infant spikes a tempretature within several hours following delivery. [Normal placental membranes] [This baby’s placental membrane] [This baby’s umbilical cord]

1. How does this baby’s membrane differ from normal extraplacental membranes?
2. What is the patholophysiology that led to this abnormality?

Case 3:

A 42 year old pregnant woman presents with vaginal bleeding at 9 weeks. On physical examination, the uterus was enlarged and fetal activity was not detected on ultrasound. [complete mole] [complete mole – gross] [complete mole]

1. Describe the features seen in the microscopic images.
2. What features distinguish a complete from a partial hydatididform mole?
3. What is the risk of subsequent choriocarcinoma in patient with a complete versus a partial hydatididform mole?

Show and Tell:

[Normal term placenta]

[Gross placenta with meconium staining]