Virtual Microscopy

 
  Virtual Microscopy > Reproductive > Gynecologic Malignancies

Case 1:

A 43 year old female was found to have a mass involving the left adnexa on a routine gynecologic exam. Transvaginal ultrasound showed a simple cystic mass. At surgery, a mass measuring 8 cm in diameter was found on the surface of the left ovary. [gross-opened benign cyst, hysterectomy/BSO, serous cystadenoma, gross of cystic tumor, mucinous cystadenoma]

  1. Describe the appearance of the lining of the cyst.
  2. Is this a benign or malignant tumor and why?
  3. What is the cell type and how does that relate to the ovarian tumor classification?

 

Case 2:

A 59 year old female presented with vague complaints of abdominal pain and increasing girth. An ultrasound showed bilateral complex solid/cystic adnexal masses, and she was immediately referred for surgical intervention. [serous cystadenocarcinoma]

  1. What gross features of this tumor are helpful in reaching the correct diagnosis?
  2. Describe the histologic features and place this tumor into its ovarian tumor subtype.
  3. What genetic mutation might be found in this woman?

 

Case 3:

A 29 year female was found to have a cystic mass on her right ovary during a C-section. A frozen section was requested. The pathologist called in to the operating room and said that the opened ovary contained a mass of hair and was partially ossified. A representative slide was reported as benign. [teratoma]

  1. What type of ovarian tumor was found?
  2. What is the pathogenesis of this type of tumor?