Virtual Microscopy	Choose another topic Cardiovascular Respiratory Renal and Urinary Tract Musculoskeletal Neuro(CNS and PNS) Gastrointestinal Reproductive Endocrine Hematopoiesis and Lymphoid Skin

Case 1:

The patient is a 67-year-old male who had a "heart attack" and cardiopulmonary arrest. Attempts at resuscitation managed to restore an irregular heartbeat for about four hours. He had a second arrest and was unsuccessfully resuscitated. He was autopsied.

Slide: [patient's brain]

Photomicrograph: [ischemic neurons]

1. Where is the histologic section taken from?
2. What cells in the central nervous system are most susceptible to anoxic damage and why might that be?
3. What abnormalities are evident in this histologic section?
4. Is the time course of this patient's problems consistent with the pathology?

Case 2:

A 72-year-old diabetic male was removing leaves from the gutter of his home on a ladder in the morning and developed sudden weakness on the left side of body. He fell from the ladder. He was taken to the emergency room and admitted to the hospital with a possible stroke. The next day, morning, the nurse found him dead in bed.

Slide: [patient's brain]

Gross photograph: [patient's brain]

Photomicrographs: [acute infarct] [subacute infarct]

1. Describe the gross findings in the brain at autopsy (see gross patient's brain)?
2. What abnormalities are evident in the histologic section?
3. What are possible etiologies for the pathologic process observed in the brain?
4. Based on the morphologic findings, approximately how old do you think the infarct is?

Case 3:

An 83-year-old woman has a history of long-standing hypertension and coronary atherosclerotic disease. She has had left sided upper extremity weakness for several years. She develops a pneumonia and dies and is autopsied.

Slides: [patient's brain]

Gross images: [patient's brain] [lacunar infarcts]

Photomicrograph: [remote infarct]

1. Describe the gross findings in the brain at autopsy (see gross patient's brain)?
2. What abnormalities are evident in the histologic sections?
3. Based on the morphologic findings, how old do you think the infarct is? Was it the cause of death in this patient?

Show & Tell Cases:

1. [gross hypertensive bleed]
2. [gross aneurysm] [aneurysm (microscopic)]
3. [gross AVM]